• Can interact with certain medications, like antidepressants and migraine medications
DB00433
buprenorphine, long-acting injection and prochlorperazine both increase sedation
dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position
Introduction Chemotherapy-induced nausea and vomiting (CINV) is one of the leading and most feared side effects of chemotherapy and can have a significant impact on patients’ quality of life during treatment
Prochlorperazine (Compazine®) binds to dopamine receptors instead of dopamine, and thereby stops the reflex to vomit
The three primary agents—ondansetron (Zofran), dolasetron (Anzemet), and granisetron
Several classes of antiemetic drugs are available that antagonize the neurotransmitter receptors known to be involved in the physiology of nausea and
Ondansetron Prochlorperazine Summary Prescription only
Ondansetron is one of the medications most commonly used for the empiric treatment of nausea and vomiting
What can I do? It is easiest to control nausea if you catch it early
A recent phase 3 clinical trial of APF530 versus Zofran, each with an NK1 antagonist and a corticosteroid, found that a single injection of APF530 maintained therapeutic levels of
25 mg IV Dolasetron 100 mg oral ONLY Tropisetron 5 mg oral or 5 mg IV Ramosetron 0
Antidepressants, anxiolytics, mood stabilizers, thyroid replacement drugs, and antihypertensives are in general safe, and do not worsen Parkinson’s disease
Compazine (Prochlorperazine): Helps treat Applies to: prochlorperazine and Zofran (ondansetron) Using prochlorperazine together with ondansetron can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect
(Zofran gave me awful headaches, and I developed an allergy to Compazine
drooling
There are no drug interactions between Zofran and Compazine, so they can be taken together
Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy
3 average score
Prochlorperazine may be used in the treatment of schizophrenia, anxiety, severe nausea, and vomiting
US Brand Name
However, both medications can have side effects, and it is important to consult with a healthcare provider before taking either medication
It has serious potential side
NVP is typically a self-limited condition and not associated with adverse pregnancy outcomes
Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy
Compazine has an average rating of 2
I found the Zofran to Evidence-Based Answer